
My father-in-law, Abraham Colton,
passed away at age 77 from Lymphoma cancer
Recent technological developments in generating biological data, such as next-generation DNA/RNA sequencing, has led to an exponential growth of biological data. This is particularly true of cancer data, as DNA sequencing is a routine procedure at many medical centers. The main bottleneck for research is therefore not in data generation but rather in interpreting this wealth of data. In our lab, we develop new algorithms and computational tools for analyzing cancer data, and apply them to the abundance of newly available data, with the goal of generating new biological insights and medical diagnostic tools.
While our interest spans all aspects of cancer bioinformatics, our current main focus is on the genomics of tumors that develop due to a deficiency in one of the DNA repair pathways.
As examples, two of the lab's current projects include:
I am a computational biologist. Chromatin structure and Epigenetics were my main fields of research during my doctoral- and postdoctoral- studies, at the Technion, and ENS - Paris. Currently I am working in Dr. Yosef Maruvka Lab on Microsatellite Instability (MSI).
My research is based on the assumption that random mutations arising during DNA replication in normal, non-cancerous stem cells may contribute to cancer development. Therefore, estimating the mutation-rate in which an individual accumulates mutations can help to predict cancer development for each individual, as well as predict characteristics of the emergence of drug resistance for each individual and each drug.
- B.Sc. in Biotechnology and Food Engineering from the Technion- Israel Institute of Technology (2020).
- Joined the team on March 2020.
Characterization of cancer by using ensemble learning algorithms.
I have received my B.Sc in Biotechnology and Food Engineering from the Technion.
My research is currently focused on better characterizing the MMR system through the analysis of different cancer types.
I have just received my B.Sc in material engineering and physics.
I am developing computational tools that can detect cancerous DNA in the cell free DNA. These tools can be used for early detection.
I am interested in the development of efficient algorithms and heuristics to model and analyze biological systems.
Currently, my research is focused on developing computational tools to deduce molecular characteristics of tumors from imaging and sequencing data
The aim of my research is to analyze the mutational pattern of 126 mammalian species, study the mutational events that shaped the evolution of those species, and compare the results with the data we have on humans.
Born in LeΓ³n, Spain. B.Sc. in Biology, M.Sc. in Innovation in Biomedicine & Health Science (University of LeΓ³n) and passionate about Mathematics, Physics and Scientific Communication as well.
My passion for science started at an early age and grew over the years.
Now, as a PhD Student at Maruvka Lab, I am willing to help people by researching in the amazing field of Cancer Bioinformatics.
As one of the greatest scientists of all times said once: βIf I have seen further, it is by standing upon the shoulder of giantsβ.
Hi!
I am Haozhen Hong from China. My Hebrew name is Sahar.
I got the B.Sc degree from GTIIT β Guangdong Technion in China and then joined the lab in October 2021.
Currently, my general research direction is to analyse AML cancer by nanopore sequencing.
I am Yu LIN, also known as Ofek, from China.
I graduated with a BSc degree in Biotechnology and Food Engineering from Guangdong Technion in 2021.
I joined Maruvka Lab as a Master's student in summer 2021.
I will take part in the laboratory and computational side of oncology research.
Hi,
I am currently working as a Research Assistant.
Hi,
I am a fourth-year B.Sc. student at the Faculty of Biotechnology and Food Engineering.
Currently, I am working on my B.Sc research project, on the topic of somatic mutations in pediatric acute myeloid leukemia.
I'm the new lab manager
I am a 2nd year Chemical Engineering Student at the Cooper Union in New York City.
I will be working in the lab under the title of "International summer intern" (summer 2021).
We have a few open positions for postdoc and Ph.D. and masters students in the wide field of cancer bioinformatics.
Curious and motivated people can apply for these positions.
All relevant backgrounds are welcome, which can range from mathematics and computer science to biology and medicine, including also physics and engineering or any other relevant training.
The most important quality we are looking for is an eagerness to learn new fields and to dive into new topics.
Please contact us at [email protected]
Our lab collaborates with a startup company Foresee Genomics in developing inexpensive and easy-to-use sequencing protocols based on Nanopore sequencing technology. Foresee Genomics develops a combined system of molecular biology and bioinformatics. An enabling technology with the purpose to increase the accuracy of the currently error-prone nanopore-based 4th generation DNA sequencing technology, transforming it into a technology that would be suitable for sensitive diagnostics. The nanopore sequencing platform is significantly inexpensive in comparison to all other NGS platforms. The combined system of Foresee Genomic and the nanopore sequencer is an end-to-end solution for genomic diagnostics which is accurate and affordable. We give labs the capability to do comprehensive molecular testing at an unprecedented price.
My father-in-law, Abraham Colton,
passed away at age 77 from Lymphoma cancer
My cousin, Dov (Irad) Eisenbach,
passed away at age 33 from tongue cancer.
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